DOT Physical Peripheral Neuropathy | Charlotte NC CDL Certification

Medically reviewed by Dr. Alan M. Tebby, D.C., FMCSA Certified Medical Examiner | Last updated: January 22, 2026

TL;DR: DOT Physical Peripheral Neuropathy

DOT physical peripheral neuropathy certification depends on severity and functional impact. Mild neuropathy with preserved sensation and motor function is generally certifiable. Severe neuropathy affecting grip strength, foot sensation, or position sense may be disqualifying if it impairs safe vehicle operation. Diabetic neuropathy is the most common cause in commercial drivers. Documentation of underlying cause, current status, and functional testing may be required. At Charlotte DOT Exam Center, we assess neuropathy’s impact on driving function. Call 704-544-3494. $70 flat rate.

Understanding Peripheral Neuropathy and Commercial Driving

Peripheral neuropathy refers to damage to the peripheral nerves, causing numbness, tingling, pain, and weakness—typically in the hands and feet. For commercial drivers, peripheral neuropathy raises concerns because adequate sensation and motor control in the extremities are essential for safe vehicle operation.

The Federal Motor Carrier Safety Administration evaluates peripheral neuropathy under 49 CFR 391.41(b)(1) and (b)(2), which require that drivers have no loss of foot, leg, hand, finger, or arm that interferes with the ability to safely control a commercial motor vehicle. This standard addresses both sensory and motor deficits.

The good news is that mild to moderate peripheral neuropathy is often compatible with commercial driving. The key factors are whether sensation and strength are adequate for safe vehicle control—not simply the presence of a neuropathy diagnosis.

Types of Peripheral Neuropathy

Sensory Neuropathy

Affects sensation, causing numbness, tingling, or altered sensation:

  • Mild numbness: May not affect driving if position sense preserved
  • Severe numbness: Loss of foot position sense is concerning for pedal control
  • Pain: Neuropathic pain may be distracting but manageable
  • Temperature insensitivity: Not typically a driving concern

Motor Neuropathy

Affects muscle strength and control:

  • Hand weakness: May affect grip on steering wheel
  • Foot drop: Difficulty lifting foot, affecting brake-to-accelerator movement
  • Muscle wasting: Indicates more severe neuropathy
  • Coordination: May affect fine motor control

Sensorimotor Neuropathy

Combined sensory and motor involvement:

  • Most common type seen in commercial drivers
  • Both sensation and strength must be evaluated
  • Overall functional impact determines certification

Autonomic Neuropathy

Affects automatic body functions:

  • Blood pressure: Orthostatic hypotension could cause dizziness
  • Heart rate: May not respond normally to stress
  • Bladder: Management issues during driving
  • Sweating: Unusual sweating patterns

FMCSA Requirements for Peripheral Neuropathy

Certification Criteria

Medical examiners evaluate neuropathy patients based on:

  • Sensory function: Adequate sensation for vehicle control feedback
  • Motor function: Sufficient strength for steering, braking, accelerating
  • Position sense: Knowing where feet are on pedals
  • Grip strength: Adequate for steering wheel control
  • Balance: Stability for getting in/out of cab, pre-trip inspection
  • Pain level: Not so severe as to impair concentration

Generally Certifiable

  • Mild sensory neuropathy with preserved motor function
  • Neuropathy limited to fingertips or toes
  • Symptoms that don’t interfere with driving function
  • Stable, non-progressive neuropathy

Potentially Disqualifying

  • Significant loss of foot position sense
  • Weakness affecting pedal operation
  • Severe hand weakness affecting steering
  • Autonomic neuropathy with orthostatic hypotension
  • Rapidly progressive neuropathy
Peripheral neuropathy is evaluated based on functional impact, not diagnosis alone.

Sensory Function Evaluation

Monofilament Testing

A common test for protective sensation, especially in diabetic neuropathy:

  • Tests ability to feel light touch
  • Inability to feel 10g monofilament indicates significant sensory loss
  • Multiple points on feet are tested
  • Results help determine degree of sensory impairment

Position Sense (Proprioception)

Critical for knowing where feet are on pedals:

  • Can you tell if your toe is being moved up or down?
  • Can you feel pedal position without looking?
  • Loss of position sense in feet is significant concern

Vibration Sense

Often one of the first sensations lost in neuropathy:

  • Tested with tuning fork
  • Loss of vibration sense indicates nerve damage
  • May correlate with other sensory loss

Pain and Temperature

  • Altered pain sensation
  • Temperature insensitivity
  • Less critical for driving than position sense

Motor Function Evaluation

Hand and Grip Strength

  • Grip dynamometer: Measures grip strength objectively
  • Minimum standards: Must grip steering wheel adequately
  • Sustained grip: Ability to maintain grip during driving
  • Fine motor control: Operating switches, controls

Foot and Ankle Function

  • Dorsiflexion: Lifting foot for brake-to-accelerator movement
  • Plantar flexion: Pressing down on pedals
  • Foot drop: Significant weakness lifting foot is concerning
  • Rapid movement: Quick transition between pedals

Functional Testing

  • Walking pattern observation
  • Heel and toe walking (tests foot strength)
  • Rising from chair without using hands
  • Tandem gait (balance)

Common Causes of Peripheral Neuropathy

Diabetic Neuropathy

The most common cause in commercial drivers:

  • Affects up to 50% of diabetics over time
  • Typically starts in feet, progresses to hands
  • Blood sugar control affects progression
  • Also evaluated under diabetes DOT requirements

See our guide on diabetes and DOT physicals.

Alcohol-Related Neuropathy

  • Results from heavy, chronic alcohol use
  • May improve with abstinence
  • Raises questions about alcohol use disorder

Vitamin Deficiency Neuropathy

  • B12 deficiency is common cause
  • Often reversible with treatment
  • Documentation of treatment is helpful

Chemotherapy-Induced Neuropathy

  • Side effect of certain cancer treatments
  • May improve after treatment ends
  • Current status is what matters for certification

Idiopathic Neuropathy

  • Unknown cause (about 30% of cases)
  • Evaluated based on functional status
  • Neurologist workup may be requested

Required Documentation for Peripheral Neuropathy

Medical Records

  • Diagnosis and likely cause of neuropathy
  • Duration and progression pattern
  • Nerve conduction study/EMG results if performed
  • Current treatment and response

Specialist Input (If Needed)

  • Neurologist evaluation for unclear or severe cases
  • Podiatrist assessment for foot involvement
  • Physical therapy functional assessment

For Diabetic Neuropathy

  • Recent A1C showing glucose control
  • Diabetes management documentation
  • Eye examination (diabetic retinopathy screening)
  • Foot examination results

FAQs: DOT Physical Peripheral Neuropathy

Can I get a CDL if I have peripheral neuropathy?

Yes, if your neuropathy is mild and doesn’t significantly impair your ability to safely control a commercial vehicle. The medical examiner assesses whether you have adequate sensation and motor function—not simply whether you have a neuropathy diagnosis.

Will numbness in my feet disqualify me?

Not necessarily. Mild numbness may be acceptable if you still have adequate position sense (knowing where your feet are on the pedals) and motor function. Severe numbness with loss of position sense is more concerning.

Do I need a neurologist letter for neuropathy?

Not always. For mild, stable neuropathy with known cause (like diabetes), the medical examiner may certify you without specialist input. More severe or unclear cases may require neurologist evaluation.

What if my neuropathy is getting worse?

Progressive neuropathy requires ongoing monitoring. You may receive shorter certificate duration to allow more frequent reassessment. Significant progression affecting function may eventually disqualify you.

How does diabetic neuropathy affect my DOT physical?

Diabetic neuropathy is evaluated as part of your overall diabetes management. Good blood sugar control, regular foot care, and stable neuropathy symptoms favor certification. Severe diabetic neuropathy with loss of protective sensation requires careful evaluation.

Will neuropathy pain medications affect my certification?

Some neuropathy medications like gabapentin or pregabalin can cause drowsiness. The medical examiner evaluates whether your medication regimen impairs alertness or driving ability.

Key Takeaways: DOT Physical Peripheral Neuropathy

  • Function over diagnosis: Certification depends on sensory/motor function, not just having neuropathy
  • Mild neuropathy often certifiable: Many drivers with mild symptoms qualify
  • Position sense critical: Must know where feet are on pedals
  • Grip strength matters: Must control steering wheel adequately
  • Cause should be identified: Diabetic, alcoholic, idiopathic, etc.
  • Progressive disease monitored: May require shorter certificate duration
  • Severe cases may need specialist: Neurologist evaluation for complex cases

Charlotte DOT Exam Center Location

Address

Charlotte DOT Exam Center
8415 Pineville-Matthews Road, Suite 102
Charlotte, NC 28226

Phone: 704-544-3494

Hours

Monday-Friday: 8:30am – 5:00pm
Saturday: 8:30am – 12:00pm

Walk-Ins Welcome

Have Neuropathy? Let Us Evaluate Your Function

Charlotte DOT Exam Center assesses neuropathy impact on commercial driving ability.

Call 704-544-3494

$70 Flat Rate • Walk-Ins Welcome • Same-Day Certification