Medically reviewed by Dr. Alan M. Tebby, D.C., FMCSA Certified Medical Examiner | Last updated: January 22, 2026
TL;DR: DOT Physical Neurological Disorders
DOT physical neurological disorders are evaluated based on FMCSA regulations that focus on whether a condition could cause sudden incapacitation, loss of consciousness, or impaired motor control while driving. Many drivers with neurological conditions can be certified with proper documentation, specialist clearance, and evidence of stable, well-controlled symptoms. Conditions like epilepsy require specific seizure-free periods, while stroke and TBI require documented recovery. At Charlotte DOT Exam Center, our FMCSA-certified examiners have extensive experience evaluating neurological conditions for commercial driver certification. Call 704-544-3494. $70 flat rate.
Understanding Neurological Conditions and DOT Physical Certification
Neurological disorders encompass a wide range of conditions affecting the brain, spinal cord, and peripheral nerves. For commercial drivers, these conditions receive careful scrutiny during DOT physical examinations because many neurological disorders can potentially cause sudden incapacitation, loss of consciousness, or impaired motor function that would make operating a commercial motor vehicle unsafe.
The Federal Motor Carrier Safety Administration (FMCSA) establishes specific medical standards under 49 CFR 391.41 that address neurological fitness for commercial driving. These regulations require that drivers not have any established medical history or clinical diagnosis of conditions likely to cause loss of consciousness or any loss of ability to control a motor vehicle safely.
This comprehensive guide provides an overview of how various neurological conditions affect DOT physical certification, including specific requirements for seizure disorders, stroke recovery, traumatic brain injury, multiple sclerosis, Parkinson’s disease, and other neurological diagnoses commonly encountered during commercial driver medical examinations in Charlotte and throughout North Carolina.
FMCSA Neurological Standards for Commercial Drivers
The FMCSA’s physical qualification standards address neurological conditions primarily through two regulatory provisions that medical examiners must carefully evaluate:
Loss of Consciousness Standard (49 CFR 391.41(b)(8))
A driver is disqualified if they have “a clinical diagnosis of epilepsy or any other condition which is likely to cause loss of consciousness or any loss of ability to control a commercial motor vehicle.” This broad standard covers numerous neurological conditions including:
- Epilepsy and all types of seizure disorders
- Narcolepsy and conditions causing excessive daytime sleepiness
- Syncope (fainting) episodes of neurological origin
- Severe vertigo and vestibular disorders causing disorientation
- Conditions causing sudden cognitive impairment or confusion
Functional Ability Standard (49 CFR 391.41(b)(1-2))
Drivers must have no impairment of limbs, hands, or fingers that interferes with the ability to control and safely drive a commercial motor vehicle. Neurological conditions affecting motor function are evaluated under this standard:
- Stroke with residual motor deficits affecting limb control
- Multiple sclerosis with functional impairment of extremities
- Parkinson’s disease affecting motor control and reaction time
- Peripheral neuropathy affecting sensation or strength in hands or feet
- Traumatic brain injury with motor sequelae affecting coordination
The FMCSA Medical Advisory Criteria and Medical Expert Panel recommendations provide additional guidance for specific neurological conditions that medical examiners use when making certification decisions for commercial drivers.
Neurological Conditions That Disqualify Commercial Drivers
Certain neurological conditions are automatically disqualifying for interstate commercial driving under standard FMCSA regulations until specific criteria are met:
Epilepsy Without Required Seizure-Free Period
Active epilepsy with recent seizures is disqualifying for commercial driving. The standard FMCSA requirement is that a driver must be seizure-free for at least 8 years and off all anti-seizure medications to qualify without an exemption. The FMCSA Seizure Exemption Program may allow certification with shorter seizure-free periods under specific conditions with ongoing monitoring requirements.
Uncontrolled Narcolepsy
Narcolepsy with cataplexy or uncontrolled excessive daytime sleepiness is disqualifying due to the high risk of sudden sleep episodes while driving a commercial vehicle. See our detailed guide on DOT physical narcolepsy for more information.
Active Intracranial Pathology
Brain tumors, active intracranial bleeding, unstable aneurysms, and other conditions with high risk of sudden neurological deterioration are disqualifying until appropriately treated and documented as stable by a neurosurgeon or neurologist.
Severe Cognitive Impairment
Dementia, severe traumatic brain injury with persistent cognitive deficits, or any condition causing significant impairment in judgment, attention, processing speed, or reaction time is disqualifying for commercial driving.
Uncontrolled Movement Disorders
Movement disorders like advanced Parkinson’s disease, essential tremor with significant amplitude, or chorea that significantly impair the ability to control vehicle steering, braking, or other critical functions are disqualifying until symptoms are adequately controlled.

Neurological Conditions That May Be Certified
Many neurological conditions can be certified for commercial driving with appropriate documentation, adequate recovery, and stability:
Stroke with Complete or Adequate Recovery
Drivers who have recovered from stroke without significant residual deficits can often be certified for commercial driving. Requirements include neurologist clearance, documentation of functional recovery, and typically a minimum waiting period based on stroke severity. See our detailed guide on DOT physical after stroke.
Traumatic Brain Injury with Documented Recovery
TBI patients who have recovered cognitive and motor function to adequate levels may be certified with neurologist clearance and comprehensive documentation of their recovery process. The waiting period and requirements depend on injury severity. See our guide on DOT physical traumatic brain injury.
Well-Controlled Migraines
Migraines without aura that do not cause sudden incapacitation are generally certifiable for commercial driving. Migraines with severe aura or that cause significant visual disturbances require more careful evaluation and neurologist documentation. See DOT physical migraines headaches.
Mild Peripheral Neuropathy
Neuropathy that does not significantly impair sensation or motor function in the extremities can be certified. The key factors are preserved position sense in feet and adequate grip strength in hands. See DOT physical peripheral neuropathy.
Stable Multiple Sclerosis
MS patients in remission or with stable, mild symptoms and adequate functional ability may be certified with neurologist clearance. Active relapses are disqualifying until resolved. See DOT physical multiple sclerosis.
Early-Stage Parkinson’s Disease
Drivers with early Parkinson’s disease that does not significantly impair driving ability may be certified with movement disorder specialist clearance. Advanced disease with significant motor or cognitive impairment is typically disqualifying. See DOT physical Parkinsons disease.
Controlled Vertigo and Vestibular Disorders
Vestibular disorders that are well-controlled and do not cause sudden incapacitating episodes may be certified with appropriate documentation. See DOT physical vertigo vestibular disorders.
Required Documentation for Neurological Conditions
Comprehensive documentation is essential for certification with any neurological condition. Proper documentation expedites the certification process and helps medical examiners make informed decisions:
Specialist Medical Records
- Neurologist evaluation report — Recent examination findings, diagnosis, and current status
- Complete treatment history — All medications, procedures, surgeries, and therapies
- Imaging studies — MRI, CT scan, MRA reports as applicable to your condition
- EEG results — Required for seizure disorders and some other conditions
- Neuropsychological testing — May be required for conditions affecting cognition
Clearance Letter Requirements
A clearance letter from your neurologist should comprehensively address:
- Specific diagnosis with date of onset or diagnosis
- Current symptom status and severity assessment
- Treatment regimen and documented compliance
- Date of last symptom occurrence (seizure, relapse, episode, etc.)
- Clear statement that driver is medically stable and cleared for commercial driving
- Any recommended restrictions, limitations, or monitoring requirements
Medication Documentation
- Complete list of all current neurological medications
- Dosages, frequency, and timing of administration
- Documentation that medications do not cause sedation or impair driving ability
- Medication compliance records if applicable
When Specialist Clearance Is Required
FMCSA medical examiners typically require neurologist clearance for the following conditions:
Always Required
- Any history of seizures or diagnosed epilepsy
- Stroke within the past 12 months or with any residual deficits
- Traumatic brain injury with loss of consciousness exceeding brief duration
- Brain surgery or any intracranial procedures
- Multiple sclerosis diagnosis regardless of current status
- Parkinson’s disease or other movement disorder diagnosis
- Narcolepsy or hypersomnia diagnosis
May Be Required Based on Severity and Presentation
- Chronic migraines with neurological symptoms or aura
- Peripheral neuropathy significantly affecting extremities
- Vertigo or vestibular disorders with recurrent episodes
- Sleep disorders with excessive daytime sleepiness
- History of transient ischemic attack (TIA)
Charlotte DOT Exam Center can advise whether specialist clearance is needed for your specific condition before your examination, potentially saving time and ensuring you arrive prepared.
Waiting Periods for Neurological Conditions
Different neurological conditions have different minimum waiting periods before certification can be considered:
| Condition | Minimum Waiting Period | Additional Notes |
|---|---|---|
| Seizure/Epilepsy (standard) | 8 years seizure-free | Off all medication; exemption program available for shorter periods |
| Stroke (ischemic) | 1-12 months | Depends on severity and documented recovery |
| Stroke (hemorrhagic) | 6-12 months | Longer wait due to higher recurrence risk |
| TBI with LOC | Variable | Based on severity classification and recovery documentation |
| Brain surgery | 6-12 months minimum | Full neurological and neurosurgical clearance required |
| TIA | 1-6 months | With negative workup and risk factor control documented |
FAQs: DOT Physical Neurological Disorders
Can I get a CDL if I have a neurological condition?
Many drivers with neurological conditions can obtain CDL medical certification. Certification depends on the specific condition, its severity, how well it’s controlled, and whether you have appropriate specialist clearance. Conditions that are stable and well-managed with documented adequate function are often certifiable.
What neurological conditions automatically disqualify me from driving commercially?
No condition is absolutely permanently disqualifying if it resolves or becomes well-controlled. However, active epilepsy with recent seizures, uncontrolled narcolepsy, severe dementia, and conditions causing sudden loss of consciousness are disqualifying until properly treated and documented as stable for required time periods.
Do I need to see a neurologist before my DOT physical?
If you have any diagnosed neurological condition, you should obtain a clearance letter from your neurologist before your DOT physical. This expedites the certification process and ensures the medical examiner has all information needed to make a determination.
Will my neurological medication disqualify me?
Most neurological medications do not automatically disqualify drivers. The medical examiner evaluates whether medications cause side effects that impair driving ability, particularly sedation. Many anti-seizure, migraine, and other neurological medications are compatible with commercial driving when properly managed.
How long will my DOT medical certificate be valid with a neurological condition?
Drivers with neurological conditions typically receive 12-month certificates requiring annual recertification for ongoing monitoring. Some stable conditions may eventually qualify for 24-month certificates. Your certificate duration depends on your specific condition, stability, and recovery status.
What if my neurological condition develops after I already have my CDL?
You must report any new neurological diagnosis to the medical examiner at your next DOT physical. Developing a disqualifying condition does not automatically revoke your CDL, but you must obtain appropriate clearance and may need to recertify more frequently. You should not drive commercially if you have symptoms that could impair safety.
Key Takeaways: DOT Physical Neurological Disorders
- Case-by-case evaluation: Most neurological conditions are evaluated individually based on function
- Specialist clearance essential: Neurologist documentation required for most conditions
- Stability is key: Well-controlled, stable conditions are often certifiable
- Waiting periods vary: Different conditions have different minimum waiting periods
- Annual certification common: Most neurological conditions require 12-month certificates
- Complete documentation critical: Bring all records, imaging, and clearance letters
- Exemption programs available: Some conditions qualify for FMCSA exemption programs
Charlotte DOT Exam Center Location
Address
Charlotte DOT Exam Center
8415 Pineville-Matthews Road, Suite 102
Charlotte, NC 28226
Phone: 704-544-3494
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Neurological Condition? We Can Help
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I am the administrator for the Charlotte DOT Exam facility, located in Charlotte NC. I oversee the facility services providing DOT exams in accordance with the standards of the FMCSA. We also provide DOT drug testing with MRO support when required. Drug testing can also be done for non-DOT exams such as pre-employment. In order to minimize wait times, I always encourage our clients to contact us first and make an appointment.
I would also suggest that each individual wanting to test for the CDL health card read the article “Preparing For Your DOT Exam” as it lists several things to bring to the test, such as CPAP usage reports and medicine lists.

















