Medically reviewed by Dr. Lemuel P. Byrd, Jr., D.C., FMCSA Certified Medical Examiner | Last updated: January 27, 2026
TL;DR: DOT Physical Amputation Limb Deficiency
Drivers with amputations or limb deficiencies can obtain CDL certification through the FMCSA Skill Performance Evaluation (SPE) Certificate program. This program requires demonstrating safe vehicle operation through a road test, regardless of limb differences. Many amputees drive commercial vehicles successfully using prosthetics or adaptive equipment. The SPE process takes 60-180 days and certification is valid for 2 years.
At Charlotte DOT Exam Center, our FMCSA-certified examiners have extensive experience evaluating this condition.
📞 Call 704-544-3494 | 💰 $70 flat rate | 🚶 Walk-ins welcome
📑 In This Guide
Understanding Amputation and Limb Deficiency and DOT Physical Certification
Amputation or limb deficiency does not automatically disqualify you from commercial driving. The FMCSA’s SPE Certificate program provides a pathway for drivers who can demonstrate safe vehicle operation despite physical differences that don’t meet standard qualification requirements.
Thousands of commercial drivers operate safely with amputations, using prosthetic devices or adaptive equipment. The key is demonstrating your ability to safely control the vehicle through the SPE road test, which evaluates your actual driving skills rather than physical appearance.
At Charlotte DOT Exam Center, we work with drivers pursuing SPE certificates and can complete the medical examination portion of your application. Our examiners understand the SPE process and can help document your functional capabilities accurately.
What Is Amputation and Limb Deficiency?
Amputation refers to the loss of a limb or part of a limb, whether from injury, disease, or congenital difference. For DOT purposes, the concern is whether you can safely operate all vehicle controls and perform required safety functions, with or without prosthetics or adaptive equipment.
How Common Is Amputation and Limb Deficiency?
Approximately 2 million Americans live with limb loss, with about 185,000 amputations performed annually. Many amputees maintain active careers including commercial driving. Advances in prosthetic technology have significantly expanded capabilities for drivers with limb differences.
FMCSA Standards for Amputation and Limb Deficiency
The FMCSA physical qualification standards are found in 49 CFR 391.49 – SPE Requirements. According to the FMCSA SPE Certificate Program, amputation and limb deficiency affects many Americans, including commercial drivers.
The FMCSA evaluates amputation and limb deficiency based on functional capacity—your ability to safely operate a commercial motor vehicle. Key factors the medical examiner considers include:
- Current condition status: Is your condition stable and well-managed?
- Functional ability: Can you perform all required commercial driving tasks?
- Medication effects: Do your medications impair driving ability?
- Safety risk: Could your condition cause sudden incapacitation?
- Documentation: Do you have adequate records supporting certification?
For additional information, see the Amputee Coalition and CDC Disability Inclusion.
Common Questions About Amputation and Limb Deficiency and CDL Certification
Commercial drivers with amputation and limb deficiency often have similar questions. Here are the most common questions we answer at Charlotte DOT Exam Center:
Can I get a CDL with an amputation?
Yes, through the FMCSA’s Skill Performance Evaluation (SPE) Certificate program. You must demonstrate safe vehicle operation through a road test. Many drivers with upper or lower limb amputations drive commercially with prosthetics or adaptive equipment.
What is the SPE Certificate?
The SPE Certificate is an FMCSA exemption that allows drivers with certain physical conditions to operate commercial vehicles after demonstrating safe driving ability through a skills test. It’s required for drivers with amputations that don’t meet standard physical qualifications.
How do I apply for an SPE Certificate?
Submit an application to FMCSA including your medical examination, description of your condition, and documentation of your ability to operate vehicle controls. You’ll then complete a road test administered by your state or an approved third party.
Can I use a prosthetic while driving commercially?
Yes, prosthetic devices are permitted for commercial driving. Your prosthetic must allow safe operation of all required controls. Document your prosthetic use and any adaptive equipment in your SPE application.
How long does the SPE process take?
The typical processing time is 60-180 days after submitting a complete application. The road test can often be scheduled before FMCSA approval, with results submitted as part of your application.
What vehicles can I drive with an SPE?
Your SPE Certificate will specify which vehicle types you’re approved to operate. Some SPEs are limited to specific configurations based on your demonstrated abilities during the road test.
How long is an SPE Certificate valid?
SPE Certificates are valid for 2 years and must be renewed. Renewal requires updated medical examination and continued demonstration of safe driving ability.
What if my amputation is recent?
For recent amputations, you’ll need to wait until you’ve adjusted to your prosthetic and can safely operate a commercial vehicle. This typically means completing rehabilitation and prosthetic training before applying for an SPE.
Amputation and Limb Deficiency and Commercial Driving Medications
Understanding which medications are compatible with commercial driving helps you prepare for your DOT physical and communicate effectively with your medical examiner.
💊 Medication Compatibility Chart
| Medication Category | Common Examples | CDL Compatible? |
|---|---|---|
| NSAIDs | Ibuprofen, naproxen (for residual limb pain) | ✅ Yes |
| Acetaminophen | Tylenol | ✅ Yes |
| Neuropathic Pain Medications | Gabapentin, pregabalin (for phantom pain) | ⚠️ Monitor for sedation |
| Topical Treatments | Lidocaine patches, capsaicin | ✅ Yes |
| Antidepressants for Pain | Duloxetine, amitriptyline (low dose for pain) | ⚠️ Monitor for sedation |
| Opioid Pain Medications | Hydrocodone, oxycodone | ❌ Generally not permitted |
✅ = Compatible | ⚠️ = Requires evaluation | ❌ = Not compatible while driving

Certification Duration Based on Amputation and Limb Deficiency Status
Your DOT medical certificate duration depends on your condition’s status, treatment effectiveness, and documentation provided:
📊 Certification by Severity
| Severity Level | Characteristics | Typical Certificate | Documentation Required |
|---|---|---|---|
| Upper limb (below elbow) | Can grip and steer with prosthetic/adaptation | SPE required | Road test + prosthetic documentation |
| Upper limb (above elbow) | May need steering adaptations | SPE required | Road test + adaptive equipment documentation |
| Lower limb (below knee) | Can operate pedals with prosthetic | SPE required | Road test + prosthetic documentation |
| Lower limb (above knee) | May need hand controls | SPE required | Road test + adaptive equipment documentation |
| Multiple limbs | Requires comprehensive adaptation | SPE required | Road test + comprehensive documentation |
⏳ Waiting Periods
| Situation | Typical Wait | Documentation Needed |
|---|---|---|
| Recent amputation | After prosthetic fitting + rehabilitation | Surgical records + rehab completion |
| Prosthetic adjustment | After stable function achieved | Prosthetist documentation |
| Revision surgery | After full recovery | Surgeon clearance |
| SPE renewal | Every 2 years | Updated medical exam + driving record |
What to Bring: Documentation Checklist
Proper documentation streamlines your DOT physical and supports certification. Gather these items before your appointment:
Required Documentation
- ✅ SPE Certificate application (Form MCSA-5876)
- ✅ DOT physical examination
- ✅ Description of amputation and functional abilities
- ✅ Road test results from approved examiner
Recommended Documentation
- 📋 Prosthetic documentation and specifications
- 📋 Adaptive equipment documentation
- 📋 Physical or occupational therapy records
- 📋 Surgeon or physiatrist clearance letter
🚨 After Hospitalization
- 🏥 Surgical records for amputation
- 🏥 Rehabilitation completion records
- 🏥 Prosthetic fitting documentation
- 🏥 Driving rehabilitation evaluation if completed
Related Conditions and Resources
Drivers with amputation and limb deficiency may have related conditions also evaluated during the DOT physical:
- DOT Physical Medical Conditions
- SPE certificate requirements
- arthritis evaluation
- chronic pain management
- post-surgery clearance
For complete information, see our DOT Physical Medical Conditions hub page.
Additional Resources
Frequently Asked Questions
Can I drive commercially with an amputation?
Yes, through the SPE Certificate program after demonstrating safe vehicle operation.
What is the SPE Certificate?
An FMCSA exemption allowing drivers with certain physical conditions to operate CMVs after passing a skills test.
Can I use a prosthetic?
Yes, prosthetics and adaptive equipment are permitted for commercial driving.
How long does the SPE process take?
Typically 60-180 days for a complete application.
How long is the SPE valid?
2 years, with renewal required.
What about recent amputations?
Wait until you’ve adjusted to your prosthetic and completed rehabilitation.
Schedule Your DOT Physical at Charlotte DOT Exam Center
Charlotte DOT Exam Center provides expert DOT physical examinations for commercial drivers with amputation and limb deficiency. Our FMCSA-certified medical examiners—Dr. Alan M. Tebby, D.C. and Dr. Lemuel Byrd—have extensive experience with this condition.
📍 Charlotte DOT Exam Center
8415 Pineville-Matthews Road, Suite 102
Charlotte, NC 28226
Monday – Friday: 8:30 AM – 5:00 PM
Saturday: 8:30 AM – 12:00 PM
Sunday: Closed
Questions? Call us at 704-544-3494 to discuss your amputation and limb deficiency and DOT certification requirements.
